26,902 research outputs found
Dynamic Moment Analysis of the Extracellular Electric Field of a Biologically Realistic Spiking Neuron
Based upon the membrane currents generated by an action potential in a
biologically realistic model of a pyramidal, hippocampal cell within rat CA1,
we perform a moment expansion of the extracellular field potential. We
decompose the potential into both inverse and classical moments and show that
this method is a rapid and efficient way to calculate the extracellular field
both near and far from the cell body. The action potential gives rise to a
large quadrupole moment that contributes to the extracellular field up to
distances of almost 1 cm. This method will serve as a starting point in
connecting the microscopic generation of electric fields at the level of
neurons to macroscopic observables such as the local field potential
Self-interaction errors in nuclear energy density functionals
When applied to a single nucleon, nuclear energy density functionals may
yield a non-vanishing internal energy thus implying that the nucleon is
interacting with itself. It is shown how to avoid this unphysical feature for
semi-local phenomenological functionals containing all possible bilinear
combinations of local densities and currents up to second order in the
derivatives. The method outlined in this Rapid Communication could be easily
extended to functionals containing higher order terms, and could serve as a
guide for constraining the time-odd part of the functional
Multispectral scanner optical system
An optical system for use in a multispectral scanner of the type used in video imaging devices is disclosed. Electromagnetic radiation reflected by a rotating scan mirror is focused by a concave primary telescope mirror and collimated by a second concave mirror. The collimated beam is split by a dichroic filter which transmits radiant energy in the infrared spectrum and reflects visible and near infrared energy. The long wavelength beam is filtered and focused on an infrared detector positioned in a cryogenic environment. The short wavelength beam is dispersed by a pair of prisms, then projected on an array of detectors also mounted in a cryogenic environment and oriented at an angle relative to the optical path of the dispersed short wavelength beam
The impact of spike timing variability on the signal-encoding performance of neural spiking models
It remains unclear whether the variability of neuronal spike trains in vivo arises due to biological noise sources or represents highly precise encoding of temporally varying synaptic input signals. Determining the variability of spike timing can provide fundamental insights into the nature of strategies used in the brain to represent and transmit information in the form of discrete spike trains. In this study, we employ a signal estimation paradigm to determine how variability in spike timing affects encoding of random time-varying signals. We assess this for two types of spiking models: an integrate-and-fire model with random threshold and a more biophysically realistic stochastic ion channel model. Using the coding fraction and mutual information as information-theoretic measures, we quantify the efficacy of optimal linear decoding of random inputs from the model outputs and study the relationship between efficacy and variability in the output spike train. Our findings suggest that variability does not necessarily hinder signal decoding for the biophysically plausible encoders examined and that the functional role of spiking variability depends intimately on the nature of the encoder and the signal processing task; variability can either enhance or impede decoding performance
What absent switch costs and mixing costs during bilingual language comprehension can tell us about language control.
Epub 2019 Mar 28.In the current study, we set out to investigate language control, which is the process that minimizes cross-language interference, during bilingual language comprehension. According to current theories of bilingual language comprehension, language-switch costs, which are a marker for reactive language control, should be observed. However, a closer look at the literature shows that this is not always the case. Furthermore, little to no evidence for language-mixing costs, which are a marker for proactive language control, has been observed in the bilingual language comprehension literature. This is in line with current theories of bilingual language comprehension, as they do not explicitly account for proactive language control. In the current study, we further investigated these two markers of language control and found no evidence for comprehension-based language-switch costs in six experiments, even though other types of switch costs were observed with the exact same setup (i.e., task-switch costs, stimulus modality-switch costs, and production-based language-switch costs). Furthermore, only one out of three experiments showed comprehension-based language-mixing costs, providing the first tentative evidence for proactive language control during bilingual language comprehension. The implications of the absence and occurrence of these costs are discussed in terms of processing speed and parallel language activation. (PsycINFO Database Record (c) 2019 APA, all rights reserved)This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 706128. This research was also supported by grants ANR-11-LABX-0036 (BLRI), ANR-16-CONV-0002 (ILCB), and ANR-11-IDEX-0001-02 from the French National Research Council (ANR)
Nonplanar integrability at two loops
In this article we compute the action of the two loop dilatation operator on
restricted Schur polynomials that belong to the su(2) sector, in the displaced
corners approximation. In this non-planar large N limit, operators that
diagonalize the one loop dilatation operator are not corrected at two loops.
The resulting spectrum of anomalous dimensions is related to a set of decoupled
harmonic oscillators, indicating integrability in this sector of the theory at
two loops. The anomalous dimensions are a non-trivial function of the 't Hooft
coupling, with a spectrum that is continuous and starting at zero at large N,
but discrete at finite N.Comment: version to appear in JHE
Emergence of slow-switching assemblies in structured neuronal networks
Unraveling the interplay between connectivity and spatio-temporal dynamics in
neuronal networks is a key step to advance our understanding of neuronal
information processing. Here we investigate how particular features of network
connectivity underpin the propensity of neural networks to generate
slow-switching assembly (SSA) dynamics, i.e., sustained epochs of increased
firing within assemblies of neurons which transition slowly between different
assemblies throughout the network. We show that the emergence of SSA activity
is linked to spectral properties of the asymmetric synaptic weight matrix. In
particular, the leading eigenvalues that dictate the slow dynamics exhibit a
gap with respect to the bulk of the spectrum, and the associated Schur vectors
exhibit a measure of block-localization on groups of neurons, thus resulting in
coherent dynamical activity on those groups. Through simple rate models, we
gain analytical understanding of the origin and importance of the spectral gap,
and use these insights to develop new network topologies with alternative
connectivity paradigms which also display SSA activity. Specifically, SSA
dynamics involving excitatory and inhibitory neurons can be achieved by
modifying the connectivity patterns between both types of neurons. We also show
that SSA activity can occur at multiple timescales reflecting a hierarchy in
the connectivity, and demonstrate the emergence of SSA in small-world like
networks. Our work provides a step towards understanding how network structure
(uncovered through advancements in neuroanatomy and connectomics) can impact on
spatio-temporal neural activity and constrain the resulting dynamics.Comment: The first two authors contributed equally -- 18 pages, including
supplementary material, 10 Figures + 2 SI Figure
Self consistent kinetic simulations of SPT and HEMP thrusters including the near-field plume region
The Particle-in-Cell (PIC) method was used to study two different ion
thruster concepts - Stationary Plasma Thrusters (SPT) and High Efficiency
Multistage Plasma Thrusters (HEMP-T), in particular the plasma properties in
the discharge chamber due to the different magnetic field configurations.
Special attention was paid to the simulation of plasma particle fluxes on the
thrusters channel surfaces. In both cases, PIC proved itself as a powerful
tool, delivering important insight into the basic physics of the different
thruster concepts. The simulations demonstrated that the new HEMP thruster
concept allows for a high thermal efficiency due to both minimal energy
dissipation and high acceleration efficiency. In the HEMP thruster the plasma
contact to the wall is limited only to very small areas of the magnetic field
cusps, which results in much smaller ion energy flux to the thruster channel
surface as compared to SPT. The erosion yields for dielectric discharge channel
walls of SPT and HEMP thrusters were calculated with the binary collision code
SDTrimSP. For SPT, an erosion rate on the level of 1 mm of sputtered material
per hour was observed. For HEMP, thruster simulations have shown that there is
no erosion inside the dielectric discharge channel.Comment: 14 pages, 11 figures This work was presented at 21st International
Conference on Numerical Simulation of Plasmas (ICNSP'09
A double coset ansatz for integrability in AdS/CFT
We give a proof that the expected counting of strings attached to giant
graviton branes in AdS_5 x S^5, as constrained by the Gauss Law, matches the
dimension spanned by the expected dual operators in the gauge theory. The
counting of string-brane configurations is formulated as a graph counting
problem, which can be expressed as the number of points on a double coset
involving permutation groups. Fourier transformation on the double coset
suggests an ansatz for the diagonalization of the one-loop dilatation operator
in this sector of strings attached to giant graviton branes. The ansatz agrees
with and extends recent results which have found the dynamics of open string
excitations of giants to be given by harmonic oscillators. We prove that it
provides the conjectured diagonalization leading to harmonic oscillators.Comment: 33 pages, 3 figures; v2: references adde
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